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Which of the following is not an objective of bioavailability studies?(a) Primary stages of development of suitable dosage form for new drug(b) Determination of the influence of excipients, patient-related factors, etc(c) Development of new formulations of the existing drugs(d) Control the quantity of the drug to be administeredThe question was posed to me in examination.This intriguing question comes from Bioavailability topic in portion Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer»

Correct answer is (d) Control the quantity of the drug to be administered

Easy explanation: More than the quantity, bioavailability studies are more used to study the quality of a drug product during the early stages of MARKETING so that the influence of processing factors, storage, and stability on drug ABSORPTION can be DETERMINED. Other objectives are the development of suitable dosage form, determination of the influence of EXCIPIENTS, patient-related factors, etc. and development of NEW formulations of the existing drugs.



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