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Which of the following is not true?(a) Paraspeckles are irregular shaped sub-nuclear compartments(b) Paraspeckles disappear in absence of RNA polemerase II transcription(c) They are transcription dependent(d) They are present during interphase and absent during mitosis.The question was asked in quiz.The query is from Nucleus in chapter Nucleus & Aerobic Respiration of Cell Biology

Answer»

Right option is (d) They are present during interphase and absent during mitosis.

Explanation: PARASPECKLES are irregular shaped sub-nuclear COMPARTMENTS which are transcription dependent.Paraspeckles disappear in absence of RNA polemerase II transcription and all of its associated protein components form a CRESCENT shaped perinucleolar cap in the nucleolus. However, paraspeckles are present during the interphase and all the STAGES of mitosis except the telophase.



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