Which of the following is the first observed tight junction proteins?(a) Zonula occludens – 1(b) Zonula occludens – β(c) Zonula occludens – A(d) Zonula occludens – αI have been asked this question during an interview.The query is from Extracellular Matrix and Cell Interactions topic in chapter Extracellular Matrix and Cell Interactions of Cell Biology

Which of the following is the first observed tight junction proteins?(

1.	Which of the following is the first observed tight junction proteins?(a) Zonula occludens – 1(b) Zonula occludens – β(c) Zonula occludens – A(d) Zonula occludens – αI have been asked this question during an interview.The query is from Extracellular Matrix and Cell Interactions topic in chapter Extracellular Matrix and Cell Interactions of Cell Biology
Answer» The correct answer is (a) Zonula occludens – 1 To elaborate: Zonula occludens – 1 was the first TIGHT JUNCTION protein discovered in the year 1986, which is abbreviated as ZO-1. This has a molecular weight of 220kDa.

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