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Which of the following is the pharmacodynamics method of studying bioavailability?(a) Acute pharmacologic response(b) Plasma-level time studies(c) Urinary excretion studies(d) Stool excretion studiesThis question was addressed to me by my college professor while I was bunking the class.My question is from Bioavailability in chapter Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer»

Right answer is (a) Acute pharmacologic RESPONSE

Explanation: Pharmacodynamic methods are a direct measurement of the drug effect on PHYSIOLOGICAL processes as a FUNCTION of time. The methods are acute pharmacologic response and therapeutic response. Pharmacokinetics method is indirect methods and these are Plasma level time STUDIES and Urinary excretion studies.



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