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Which of the following is untrue about ConSite?(a) It is a web server that finds putative promoter elements(b) It includes comparing two orthologous sequences(c) The program does not accept pre-computed alignment(d) The program accepts pre-computed alignmentThis question was posed to me in homework.My question is based upon Prediction Algorithms in section Promoter and Regulatory Element Prediction of Bioinformatics

Answer»

The correct answer is (c) The PROGRAM does not accept pre-computed alignment

The best explanation: The USER provides two individual sequences which are aligned by ConSite using a global alignment algorithm. Conserved REGIONS are identified by calculating identity scores, which are then used to compare against a motif database of REGULATORY sites (TRANSFAC). High-scoring sequence segments upstream of genes are returned as putative regulatory elements.



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