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Which of the molecule in photolyase acts as an electron donor for recovery of the CPD?(a) NADH(b) FADH-(c) MTHF poly Glu(d) NAD+The question was posed to me during an interview.This intriguing question originated from Repair of DNA Damage: NER, Direct Reversal in portion DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer»

The correct ANSWER is (b) FADH-

The best I can explain: When the chromophore MTHF poly Glu receives the UV light, it passes the energy on to FADH- which in turn passes the electron to CPD. The electron helps in rearrangement of the BONDS in CPD and RETURNS them to the form of two pyrimidine residues.



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