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Which of the mutations can be detected Phenotypically?(a) Silent(b) Neutral(c) Reverse(d) SenseThe question was posed to me in an interview for job.The origin of the question is DNA Mutation in chapter DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer»

Correct answer is (d) SENSE

The best I can explain: All the other MUTATION LEAD to wild phenotype, so unless a GENETIC analysis is performed, they are indistinguishable. But in case of sense a stop codon is changed to a coding codon which has a serious phenotypic effect on the protein.



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