Which of this mutagen can lead to both AT->GC and GC->AT transition?(a) Ethydium bromide(b) 5 Bromo uracil(c) MMS(d) NH2OHI got this question in an online interview.The question is from DNA Mutation in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Which of this mutagen can lead to both AT->GC and GC->AT transition?(a

1.	Which of this mutagen can lead to both AT->GC and GC->AT transition?(a) Ethydium bromide(b) 5 Bromo uracil(c) MMS(d) NH2OHI got this question in an online interview.The question is from DNA Mutation in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics
Answer» Correct ANSWER is (b) 5 Bromo uracil For explanation I would say: 5 Bromo Uracil when incorporates in the DNA in a NORMAL state and then undergoes TRANSITION to a rare state in the next replication cycle leads to an AT->GC MUTATION. While when it incorporates against a G in excited state and then undergoes replication when in the normal state it gives GC->AT transition.

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Which of this mutagen can lead to both AT->GC and GC->AT transition?(a) Ethydium bromide(b) 5 Bromo uracil(c) MMS(d) NH2OHI got this question in an online interview.The question is from DNA Mutation in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

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