Which one of these are correct Michaelis-Menten equation?(a) –dC/dt = Vmax C/Km+C(b) dC/dt = Vmax C/Km+C(c) –dC/dt = Vmax C/Km(d) –dC/dt = Km+C/Vmax CThe question was asked during an online exam.Query is from Non Linearity of Drugs in chapter Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Which one of these are correct Michaelis-Menten equation?(a) –dC/dt

1.	Which one of these are correct Michaelis-Menten equation?(a) –dC/dt = Vmax C/Km+C(b) dC/dt = Vmax C/Km+C(c) –dC/dt = Vmax C/Km(d) –dC/dt = Km+C/Vmax CThe question was asked during an online exam.Query is from Non Linearity of Drugs in chapter Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology
Answer» Right option is (a) –dC/dt = Vmax C/Km+C To explain: The kinetics of capacity-limited or saturation process is DESCRIBED by Michaelis-Menten equation, the equation is –dC/dt = Vmax C/Km+C, where –dC/dt = rate of decline of DRUG concentration with TIME, Vmax is the THEORETICAL maximum rate of the process and Km is Michaelis constant.

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