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Which organ comprises the peripheral compartment in a two compartment model?(a) Liver(b) Lungs(c) Kidneys(d) MusclesThis question was addressed to me during an interview.I need to ask this question from One & Two Compartment Open Model in division Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer»

Right choice is (d) MUSCLES

For explanation: The PERIPHERAL compartment or compartment 2 in a two compartment model comprises of POORLY perfused and slowly equilibrating tissues such as muscles, skin, adipose tissue, etc. These are considered as a HYBRID of several functional physiologic units.



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