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Which part of the proteasome recognizes a polyubiquitinated protein?(a) alpha-subunit(b) beta-subunit(c) gamma-subunit(d) end capsThe question was posed to me in homework.I need to ask this question from Gene Expression Control topic in portion Control of Gene Expression of Cell Biology

Answer»

Correct option is (b) beta-subunit

To explain I WOULD say: Once the protein is polyubiquitinated, it is ready for enzymatic degradation by the PROTEASOME. The cap of proteasome RECOGNIZES the protein and REMOVES the ubiquitin CHAIN and unfolds the target protein.



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