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Which type of fermentation is preferred in bench top fermenter?(a) Batch(b) Fed-batch(c) Continuous(d) Dual or multiple-fermentationI got this question in an interview for job.The query is from Steps in Bioprocess Development : A Typical New Product from Recombinant DNA in section Bioprocess Development of Bioprocess Engineering

Answer»

Correct answer is (b) Fed-batch

For explanation: Fed-batch fermentation is superior to conventional batch fermentation when CONTROLLING CONCENTRATIONS of a nutrient (or NUTRIENTS) affect the yield or productivity of the desired metabolite. The advantage of the fed-batch fermentation is that one can control concentration of fed-substrate in the culture liquid at arbitrarily desired LEVELS.



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