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Who has poorly developed BBB?(a) Infants(b) Adults Of age more than 20(c) Aged(d) Children at pubertyI have been asked this question in semester exam.My question is from Drug Distribution topic in division Distribution of Drugs of Drug Biotechnology

Answer»

Right ANSWER is (a) Infants

Explanation: Infants are newly BORN. Their BBB is poorly developed. The myelin content is LOW but the cerebral blood FLOW is very high. Thus LEADING to the high penetrating ability of the drugs into the brain of infants.



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