

InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
51. |
Which of the following is wrong about diplotene?(a) Endoplasmic vesicles increase in the number(b) Nucleolus condenses(c) Chromatid body is seen(d) Chromosomes rotate by 180 degree to terminalizeThis question was posed to me by my school teacher while I was bunking the class.Query is from Meiosis Prophase 1 : Diplotene and Diakinesis topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT OPTION is (b) Nucleolus condenses |
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52. |
What is the stretch of DNA remaining unreplicated during pachytene?(a) 200bp(b) 1000bp(c) 104bp(d) 10 kbThis question was addressed to me in my homework.Question is from Meiosis Prophase 1 : Pachytene in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» RIGHT OPTION is (a) 200bp Best explanation: In pachytene stage short stretches of DNA remains unreplicated. This is as short as 200bp. In ZYGOTENE stage the unreplicated chromosomes are about 104 bp. |
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53. |
In an experiment you introduce a pair of unpaired homologous chromosomes into pachytene stage, what will you expect to observe?(a) Pairing and subsequent recombination(b) Pairing will occur but no recombination(c) No pairing will occur but recombination will take place(d) Neither pairing nor recombinationI have been asked this question in an internship interview.I would like to ask this question from Meiosis Prophase 1 : Pachytene topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT choice is (d) Neither pairing nor RECOMBINATION |
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54. |
The fibers of the lateral filament are called____________(a) Synaptomes(b) Synaptomere(c) Synaptic clefts(d) SynaptososomeI have been asked this question during an internship interview.My question is from Meiosis Prophase 1 : Synaptonemal Complex topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right answer is (b) SYNAPTOMERE |
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55. |
Nuclear envelope breaks down finally in _____________(a) Prophase(b) Pro metaphase(c) Metaphase(d) AnaphaseThis question was posed to me during an online interview.This is a very interesting question from Meiosis 1 Metaphase, Anaphase & Telophase topic in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right CHOICE is (B) Pro metaphase |
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56. |
What is the normal number of chiasma seen in diplotene chromosomes?(a) 2(b) 4(c) 8(d) 16The question was asked in an online interview.My question is based upon Meiosis Prophase 1 : Diplotene and Diakinesis in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT option is (b) 4 |
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57. |
If the pairing starts at terminal and proceeds towards centre it is known as ________________(a) Procentric(b) Proterminal(c) Random(d) AcrocentricI have been asked this question in an online interview.The query is from Meiosis Prophase 1 : Zygotene topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct answer is (b) Proterminal |
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58. |
What is the bivalent shape in diakinesis?(a) X shaped(b) O shaped(c) Y shaped(d) Star shapedI had been asked this question in an interview.My question is from Meiosis Prophase 1 : Diplotene and Diakinesis in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right choice is (b) O SHAPED |
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59. |
The pairing of the chromosome is mediated by _______________ interactions.(a) Hydrophilic(b) Hydrophobic(c) Covalent(d) ElectrostaticI got this question during an interview.This intriguing question comes from Meiosis Prophase 1 : Synaptonemal Complex topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» CORRECT OPTION is (d) ELECTROSTATIC The best I can explain: The tails of TWO opposite zygosomes are oppositely charged. This brings about pairing by electrostatic interaction. |
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60. |
The formation of synaptonemal complex is ______________ DNA replication in zygotene.(a) Before(b) Simultaneous(c) After(d) Unrelated toI got this question in quiz.My question is from Meiosis Prophase 1 : Zygotene topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct choice is (c) After |
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61. |
Pairing of chromosome is initiated by hydrodynamic force.(a) True(b) FalseI have been asked this question during an interview for a job.My query is from Meiosis Prophase 1 : Zygotene in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» CORRECT option is (a) True To EXPLAIN I would say: Due to vibrations in the CYTOSOL the CHROMOSOMES PAIR. This pairing is mainly due to hydrodynatic force. Another theory for pairing is via electrostatic force. |
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62. |
Which of the following is true?(a) Zygotene is the phase preceding diplotene(b) DNA replicated in zygotene is incorporated in chromosome 5-6 days later(c) Synaptonemal complex formed is longer than the physical length of chromosomes itself(d) The pairing of chromosomes forces the DNA to replicateThis question was posed to me in an international level competition.Origin of the question is Meiosis Prophase 1 : Zygotene topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct OPTION is (b) DNA replicated in zygotene is incorporated in chromosome 5-6 days later |
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63. |
The point where the synaptonemal complex is attached to nuclear envelope is called _______________(a) Bouque stick(b) Meiotic point(c) Fixation point(d) TelomerinI had been asked this question in exam.The query is from Meiosis Prophase 1 : Pachytene topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct CHOICE is (c) Fixation point |
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64. |
Chromosomal compaction is brought about by________(a) Cohesin(b) Thrombin(c) Condensin(d) SequrinThis question was posed to me in exam.The doubt is from Mitosis Stages Overview in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT choice is (c) Condensin |
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65. |
What is a negative regulator of Cdc-20?(a) M-Cdk(b) Mad-2(c) Mdm(d) Hct1This question was posed to me during a job interview.My doubt stems from Overview of Cell Reproduction in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Correct ANSWER is (b) Mad-2 |
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66. |
Which of the following is an activation process?(a) Wee1 kinase(b) APC(c) Cdc25(d) p27 bindingThe question was posed to me during an interview.I want to ask this question from Overview of Cell Reproduction topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right option is (c) Cdc25 |
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67. |
Eggs in female stay in ______________ phase for extended duration.(a) S(b) G1(c) G2(d) MThis question was addressed to me in final exam.Enquiry is from Overview of Cell Reproduction topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» RIGHT answer is (d) M For explanation I would say: Eggs are stored for long in the ovary in the diplotene STAGE of meiosis 1 KNOWN as dichtyotene. Then the chromosomes are paired ACCORDING to the homologous pairing. |
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68. |
In haploid organism meiosis takes place in _____________(a) Somatic cell(b) Zygote(c) Gamete(d) EggI had been asked this question in class test.My question is from Meiosis Prophase 1 : Leptotene in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» RIGHT option is (B) Zygote Easy explanation: In haploid organisms the zygote is DIPLOID which undergoes meiosis to give a haploid individual. Here, egg and other GAMETE are haploid as is somatic cell, so no meiosis is required by it. |
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69. |
Is it true that a cell can keep on replicating forever?(a) True(b) FalseI have been asked this question at a job interview.I need to ask this question from Mitosis Stages Overview topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right choice is (b) False |
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70. |
We know that caffeine helps to overcome M-Cdk activation checkpoint. What will be the fate of the cell treated with hydroxyl urea and caffeine in G1 phase?(a) Cell will not divide(b) Cell will become smaller in size(c) Cell will divide with improper chromosome number(d) Cell will undergo lysisI have been asked this question in an international level competition.The above asked question is from Overview of Cell Reproduction in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right OPTION is (c) CELL will divide with improper chromosome number |
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71. |
In an experiment you increase the concentration of Cln3. What will be its effect on proliferating yeast cells?(a) Cells will be smaller in size(b) Cells will still have normal size(c) Cells will increase in size(d) Cells will die offI had been asked this question in class test.This question is from Overview of Cell Reproduction topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right option is (a) Cells will be smaller in SIZE |
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72. |
Which of the following will prevent cell cycle from progressing in case of DNA damage?(a) P53(b) G1 cyclin(c) P10(d) Bcl-2I have been asked this question during a job interview.I'd like to ask this question from Overview of Cell Reproduction topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct option is (a) P53 |
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73. |
If a permanent cell re enters cell cycle it is ______________(a) Differenciation(b) Redifferenciation(c) Dedifferenciation(d) ApoptosisI have been asked this question in exam.The doubt is from Mitosis Stages Overview topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT answer is (C) DEDIFFERENCIATION |
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74. |
In cells the DNA replication takes place in _____________ phase.(a) G0(b) G1(c) S(d) G2I have been asked this question in unit test.The origin of the question is Overview of Cell Reproduction topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The CORRECT option is (c) S |
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75. |
The concentration of which of the following varies during the cell cycle?(a) Cdk(b) Cyclin(c) SCF(d) ProteosomeThis question was posed to me in a job interview.The doubt is from Overview of Cell Reproduction topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct option is (b) CYCLIN |
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76. |
The cells before permanently differentiating enters into ______________ phase.(a) G1(b) G2(c) G0(d) SThe question was posed to me in a national level competition.I want to ask this question from Overview of Cell Reproduction in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct answer is (c) G0 |
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77. |
Cdc20___________________ anaphase.(a) Promotes(b) Prevents(c) Slows(d) Unrelated toThe question was posed to me in examination.My enquiry is from Mitosis Stages Overview topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Correct option is (a) Promotes |
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78. |
Which of the following true about Rb in the cell cycle?(a) Phosphorylation of Rb will lead to its inactivation(b) Phosphorylation of Rb will also lead to inactivation of E2F(c) Phosphorylation of E2F will promote cell cycle progression(d) E2F is directly affected by RbThe question was posed to me by my school principal while I was bunking the class.This is a very interesting question from Overview of Cell Reproduction topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right choice is (B) Phosphorylation of Rb will also LEAD to inactivation of E2F |
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79. |
Meiosis is called reduction division.(a) True(b) FalseI have been asked this question during a job interview.The query is from Meiosis Prophase 1 : Leptotene topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct choice is (a) True |
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80. |
_________________ follows __________________(a) Karyokinesis, mitosis(b) Cytokinesis, Karyokinesis(c) Mitosis, Karyokinesis(d) Karyokinesis, CytokinesisI had been asked this question by my college director while I was bunking the class.The question is from Mitosis Stages Overview topic in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct choice is (B) CYTOKINESIS, Karyokinesis |
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81. |
If you use colchicines, which of the cell division phases is prevented?(a) DNA replication(b) Prophase(c) Anaphase(d) TelophaseI got this question in an interview for internship.I want to ask this question from Mitosis Stages Overview in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» CORRECT choice is (c) Anaphase Easy explanation: Colchicine disrupts the microtubule structure which leads to the ABSENCE of anaphase. While DNA replication is not prevented, so colchicines can EFFECTIVELY lead to chromosomal DOUBLING. |
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82. |
Anaphase is brought about by the change in which cytoskeletal element?(a) Tubulin(b) Actin(c) Myosin(d) DyaninThe question was asked during a job interview.The query is from Mitosis Stages Overview in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct answer is (a) TUBULIN |
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83. |
The inactivation of M-Cdk is through the Cdc20-APC activity, what activates Cdc-20-APC?(a) G1-Cdk(b) G1-S-Cdk(c) S-Cdk(d) M-CdkThe question was asked in final exam.This intriguing question comes from Overview of Cell Reproduction in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right answer is (d) M-Cdk |
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84. |
P53 requires ________________for its activity.(a) Mdm(b) MCM(c) Securin(d) CdtThis question was addressed to me during an interview.I would like to ask this question from Overview of Cell Reproduction in section Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right choice is (a) MDM |
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85. |
Which of the following doesn’t take place in prophase if mitotic cell?(a) Chromosome starts to contract(b) The nuclear membrane breaks down(c) The nucleolus disappears(d) The chromosomes pair up with their homologueThe question was asked in a job interview.My question is from Mitosis Stages Overview topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» RIGHT answer is (d) The chromosomes pair up with their homologue To elaborate: Chromosomal PAIRING is a CHARACTERISTIC of meiotic cell not MITOTIC cell. Most of the steps in PROPHASE of meiosis and mitosis being the same we observe the rest of the steps in mitotic prophase. |
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86. |
If your chromosome is submetacentric, what will be the anaphase shape while separation?(a) I(b) J(c) L(d) VThis question was posed to me during an internship interview.Question is from Mitosis Stages Overview topic in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» CORRECT option is (c) L The best I can explain: During anaphase separation the chromatins are under a FORCE, they tend to formL SHAPED structure if they are metacentraic. I, J and V STRUCTURES are formed by telocentric, acrocentric and metacentric CHROMOSOMES respectively. |
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87. |
Which one of the following doesn’t help in degrading cohesion?(a) Cdc20(b) M-Cdk(c) Securin(d) SeparaseI have been asked this question during an interview.My question comes from Mitosis Stages Overview in chapter Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct choice is (C) Securin |
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88. |
The reduction division of mitosis is _________________(a) The 1^st division(b) The 2^nd division(c) The G2 phase(d) The telophaseThis question was addressed to me in a job interview.The query is from Meiosis Prophase 1 : Leptotene topic in portion Chromosomal Changes During Meiosis of Cytogenetics |
Answer» The correct answer is (a) The 1^st division |
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89. |
Mitosis occurs in _________(a) Nephron(b) Hair follicles(c) Neurons(d) OvaryThe question was posed to me during an interview.Question is taken from Mitosis Stages Overview topic in division Chromosomal Changes During Meiosis of Cytogenetics |
Answer» Right choice is (b) Hair follicles |
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