InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
Who was the first person to develop DNA finger printing?(a) David Suzuki(b) Khorana(c) Alec Jaffreys(d) Gilbert |
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Answer» The correct choice is (c) Alec Jaffreys The explanation: Alec Jaffreys was the first person to develop DNA finger printing. |
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| 102. |
The precise biochemical activity of a protein is described in __________(a) Phenotypic function(b) Cellular function(c) Molecular function(d) Structural genomics |
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Answer» Right answer is (c) Molecular function The best I can explain: Structural genomics, it includes sequencing of genomic DNA. Phenotypic function, it describes the effects of protein on an entire organism. Cellular function, it describes about the network of interactions engaged in by protein at cellular level. |
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| 103. |
Native state of a protein can be disrupted by __________(a) Temperature(b) pH(c) Removal of water(d) Presence of hydrophilic surfaces |
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Answer» The correct answer is (d) Presence of hydrophilic surfaces The best I can explain: Native state of a protein can be disrupted by temperature, pH, Removal of water and presence of hydrophobic surfaces. |
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| 104. |
What is the goal of structural proteomics project?(a) To crystallize and determine the structure of as many proteins as possible, in many cases with little or no existing information about protein function(b) To identify and sequence of all the genes present in the human body(c) To introduce new genes to human beings(d) To remove disease causing genes from humans |
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Answer» Right choice is (a) To crystallize and determine the structure of as many proteins as possible, in many cases with little or no existing information about protein function The explanation is: Options b, c, d comes under the goals of human genomic project. |
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| 105. |
The effects of protein on an entire organism is described in __________(a) Phenotypic function(b) Cellular function(c) Molecular function(d) Structural genomics |
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Answer» The correct option is (a) Phenotypic function Easiest explanation: Cellular function, it describes about the network of interactions engaged in by protein at cellular level. Molecular function, it describes the precise biochemical activity of a protein. Structural genomics, it includes sequencing of genomic DNA. |
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| 106. |
Long-chain fatty acids are oxidized step-wise in one carbon unit starting from ____________(a) Carboxyl end(b) Aliphatic end(c) Carboxyl and Aliphatic end(d) None of the mentioned |
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Answer» Right answer is (a) Carboxyl end The explanation: Long-chain fatty acids are oxidized step-wise in one carbon unit starting from carboxyl end. |
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| 107. |
Photosynthesis can be described as ____________(a) Reductive, anabolic, endergonic process(b) Reductive, anabolic, exergonic process(c) Oxidative, anabolic, endergonic process(d) Oxidative, catabolic, exergonic process |
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Answer» The correct answer is (a) Reductive, anabolic, endergonic process To explain: Photosynthesis involves gaining of electrons; producing complex substances from simpler ones and requires energy. |
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| 108. |
What is the general term used for the anaerobic degradation of glucose to obtain energy?(a) Anabolism(b) Oxidation(c) Fermentation(d) Metabolism |
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Answer» The correct choice is (c) Fermentation To explain I would say: Fermentation is the general term used for the degradation of glucose to obtain energy in the form of ATP. |
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| 109. |
NADP is a cofactor used in ____________(a) Catabolic reactions(b) Anabolic reactions(c) Elimination reaction(d) Redox reactions |
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Answer» Right option is (b) Anabolic reactions Explanation: NADP is a cofactor used in anabolic reactions. |
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| 110. |
Which out of the following enzymes can utilize both NAD^+ and NADP^+ as a coenzyme?(a) Glutamate dehydrogenase(b) Alcohol dehydrogenase(c) Aldehyde dehydrogenase(d) Glycerol-3-P dehydrogenase |
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Answer» The correct option is (a) Glutamate dehydrogenase Explanation: Only Glutamate dehydrogenase can utilize both NAD^+ and NADP^+ as a coenzyme. |
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| 111. |
Which of the following is not a condensation reaction?(a) ADP + inorganic phosphate ATP + H2O(b) R-OH + inorganic phosphate phosphate ester + H2O(c) R-COOH + inorganic phosphate Acyl phosphate + H2O(d) 6CO2 + 6 H2O C6H12O6 + 6CO2 |
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Answer» Correct answer is (d) 6CO2 + 6 H2O C6H12O6 + 6CO2 Easiest explanation: Condensation reaction involves elimination of water molecules. |
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| 112. |
Which of the following is a component of mitochondria?(a) Ribonuclease(b) Lysozyme(c) Cytochrome c(d) Myoglobin |
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Answer» Right answer is (c) Cytochrome c The best explanation: Cytochrome c which is a heme protein is a component of the respiratory chain of mitochondria. |
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| 113. |
The salt which produces salting out effect during extraction of proteins is?(a) NH4 SO4(b) (NH4)2 SO4(c) (NH4)3 SO4(d) NaCl |
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Answer» Right option is (b) (NH4)2 SO4 Easiest explanation: (NH4)2 SO4 is added in the right amount can selectively precipitate some proteins, while others remain in the solution. (NH4)2 SO4 is often used for this purpose because of its high solubility in water. |
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| 114. |
In cell membranes, carbohydrates in glycoproteins or glycolipids are oriented?(a) Towards outside(b) Towards inside(c) Towards outside and inside(d) Randomly distributed |
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Answer» Right choice is (a) Towards outside Easiest explanation: The orientation of carbohydrates in glycoproteins is towards outside in cell membranes. |
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| 115. |
Which of the following hydrolyzes successive amino-terminal residues from short peptides?(a) Aminopeptidase(b) Enteropeptidase(c) Glutamine synthase(d) Glutamate dehydrogenase |
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Answer» The correct choice is (a) Aminopeptidase Easiest explanation: Aminopeptidase hydrolyzes successive amino-terminal residues from short peptides. |
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| 116. |
Anabolism and catabolism are chemically linked in the form of __________(a) ADP(b) ATP(c) Phosphodiester linkage(d) ASP |
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Answer» Correct option is (b) ATP Easiest explanation: Anabolism is an energy intake process where small molecules build upto large molecules whereas catabolism involves the release of energy where large molecules tear down to smaller molecules. |
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| 117. |
Depolarization and repolarization changes that occur during the action potential are produced by ____________(a) Negative feedback loops(b) Carrier mediated transport(c) Simple diffusion of ions down their concentration gradient(d) Active transport pumps along the neuron membrane |
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Answer» The correct option is (d) Active transport pumps along the neuron membrane Easy explanation: Na^+ channels open at the beginning of action potential and moves into the axon causing depolarization, when K^+ channels open repolarization takes place and moves out of the axon. |
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| 118. |
What makes water a liquid at room temperature?(a) Hydrogen bonds between water molecules(b) Covalent bonding(c) Noncovalent interactions(d) Van der Waals forces of attraction |
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Answer» Correct choice is (a) Hydrogen bonds between water molecules Easy explanation: Hydrogen bonds between water molecules provide the cohesive forces that make water a liquid at room temperature. |
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| 119. |
Fibroin is rich in ________(a) Alanine and Glycine(b) Alanine(c) Glycine(d) Pro |
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Answer» Right answer is (a) Alanine and Glycine To elaborate: Fibroin is rich in Alanine and Glycine residues, permitting a close packing of β sheets and an interlocking arrangement of R groups. |
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| 120. |
The factor which does not affect pKa value of an amino acid is _________(a) The loss of charge in the α-carboxyl and α-amino groups(b) The interactions with other peptide R groups(c) Other environmental factors(d) Molecular weight |
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Answer» Correct choice is (d) Molecular weight To elaborate: The loss of charge in the α-carboxyl and α-amino groups, the interactions with other peptide R groups and other environmental factors can affect the pKa. |
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| 121. |
The degree of ionization does not depend on?(a) Temperature(b) Current(c) Nature of solvent(d) Concentration |
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Answer» Correct answer is (b) Current For explanation I would say: Degree of ionization is independent of current. It depends only on temperature, nature of solvent and concentration. |
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| 122. |
ΔH is positive for which of the following processes?(a) Oxidation of nitrogen(b) Melting of ice and evaporation of water(c) Oxidation of gold(d) Burning of chlorine |
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Answer» Correct answer is (b) Melting of ice and evaporation of water Explanation: Enthalpy change (ΔH) is positive for endothermic reactions, the reactions which involves absorption of energy. Melting of ice and evaporation of water involves absorption of energy. |
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| 123. |
What best summarizes the MALDI method by which gas phase ions are produced for mass spectrometry?(a) Sample is hit by a low energy xenon beam(b) Sample is forced through a narrow capillary tube and the solvent rapidly evaporates(c) Sample is embedded in a crystalline matrix and bombarded by laser beams(d) Sample is heated and then bombarded by electrons |
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Answer» Right answer is (c) Sample is embedded in a crystalline matrix and bombarded by laser beams The best explanation: MALDI, the term itself is an abbreviation for Matrix Assisted Laser Desorption or Ionization. |
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| 124. |
Which of the following is the largest immunoglobulin?(a) IgA(b) IgE(c) IgG(d) IgM |
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Answer» Right choice is (d) IgM To explain: IgM is the largest pentameric type of antibody in the human circulatory system. |
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| 125. |
Which among the following is both glucogenic and ketogenic?(a) Isoleucine(b) Leucine(c) Lysine(d) Histidine |
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Answer» Correct choice is (a) Isoleucine To explain: Isoleucine produces both glucose and ketone bodies as an energy source. |
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| 126. |
The backbone of phospholipids is __________(a) L-glycerol 1-phosphate(b) L-glycerol 3-phosphate(c) D-glycerol 3-phosphate(d) sn-glycerol 1-phosphate |
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Answer» The correct option is (b) L-glycerol 3-phosphate The explanation: L-glycerol 3-phosphate or D-glycerol 1-phosphate or sn-glycerol 3-phosphate is the backbone of phospholipids. |
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| 127. |
Hemoglobin is a __________(a) Monomer(b) Dimer(c) Trimer(d) Tetramer |
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Answer» The correct option is (d) Tetramer Easiest explanation: It is a tetramer with 2 α chains and 2β chains. |
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| 128. |
Number of chiral centers in isoleucine is?(a) 1(b) 2(c) 3(d) 4 |
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Answer» Right answer is (b) 2 To elaborate: H5 C2 – C ̇H(CH3)- C ̇H(NH2) – COOH The structure clearly shows two chiral centers of isoleucine. |
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| 129. |
Which of the following statements is true about affinity chromatography?(a) During the separation of a mixture of proteins, the protein which does not bind to ligand is eluted first(b) During the separation of a mixture of proteins, the protein which does not bind to ligand is eluted last(c) During the separation of a mixture of proteins, the protein which binds to ligand is eluted first(d) Unwanted proteins are eluted by ligand solution |
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Answer» The correct answer is (a) During the separation of a mixture of proteins, the protein which does not bind to ligand is eluted first To explain I would say: After proteins that do not bind to the ligand are washed through the column, the bound protein of particular interest is eluted. |
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| 130. |
The pattern on paper in chromatography is called __________(a) Chroming(b) Chroma(c) Chromatograph(d) Chromatogram |
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Answer» Right option is (d) Chromatogram The best explanation: In paper chromatography usually stationary phase is a strip of chromatography paper which is also called a chromatogram. |
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| 131. |
Which of the following statements is true about ion-exchange chromatography?(a) It separates proteins according to their size(b) The column matrix with bound anionic groups is called cationic exchanger(c) The column matrix with bound anionic groups is called anionic exchanger(d) The column matrix with bound cationic groups is called cationic exchanger |
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Answer» The correct choice is (b) The column matrix with bound anionic groups is called cationic exchanger Explanation: It involves the attachment to the column matrix of ionic groups known that bind to the anted protein. Cationic exchanger exchanges cations with anionic groups. |
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| 132. |
One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle.(A) 6 (B) 3 (C) 1 (D) 2 |
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Answer» The correct option is (A) 6. One molecule of glucose gives 6 molecules of CO2 in EM-TCA cycle. |
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| 133. |
In which of the following, glucose residues are linked by β1 &arr; 4 glycosidic bonds?(a) Amylose(b) Starch(c) Cellulose(d) Glycogen |
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Answer» The correct option is (c) Cellulose The best I can explain: The glucose residues in cellulose are linked by β1 &arr; 4 glycosidic bonds, in contrast to the α1 &arr; 4 bonds of amylose, starch and glycogen. |
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| 134. |
Number of hydrogen bonds between adenine and thymine?(a) 1(b) 2(c) 3(d) 4 |
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Answer» Correct choice is (b) 2 Easy explanation: A = T is the notation for bonding between A and T. |
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| 135. |
What is a DNA library?(a) A DNA fragment inserted into a vector(b) A general collection of all genes sequenced thus far(c) All DNA fragments identified with a probe(d) A collection of DNA fragments that make up the entire genome of a particular organism |
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Answer» Correct choice is (d) A collection of DNA fragments that make up the entire genome of a particular organism Best explanation: DNA library is a collection of DNA fragments representing the entire DNA of an organism. |
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| 136. |
Production of a large number of genetically similar plants through plant tissue culture is called __________(a) Recombinant DNA technology(b) Gene therapy(c) Micro propagation(d) Hybridoma technology |
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Answer» Correct choice is (c) Micro propagation The best explanation: Micro propagation is the practice of producing a large number of genetically similar plants through plant tissue culture. |
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| 137. |
In cholera there is uncontrolled secretion of _________(a) Na^+ and H2O(b) K^+ and H2O(c) Ca^+2 and H2O(d) Mg^+2 and H2O |
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Answer» Right option is (a) Na^+ and H2O Explanation: There is an uncontrolled secretion of Na^+ and H2O in the intestine. |
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| 138. |
Which of the following serves as bactericidal agent?(a) Ribonuclease(b) Lysozyme(c) Cytochrome c(d) Myoglobin |
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Answer» The correct choice is (b) Lysozyme To explain I would say: Lysozyme can lyse, or degrade bacterial cell walls, so it serves as a bactericidal agent. |
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| 139. |
Which is an example of negative regulator?(a) CAP(b) Lac 1 gene(c) Nuclear receptors(d) Phosphorylated STAT proteins |
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Answer» Right answer is (b) Lac 1 gene Best explanation: CAP, Nuclear receptors and Phosphorylated STAT proteins are positive regulators. |
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| 140. |
Sarcomere is a part between __________(a) 2 I bands(b) 2 Z bands(c) 2 A bands(d) 2 H bands |
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Answer» Right choice is (b) 2 Z bands The explanation is: Z lines are formed between adjacent sarcomeres. |
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| 141. |
Negative regulator of ethylene response is _________(a) LPS(b) CTR1(c) BAK1(d) MAPK |
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Answer» The correct option is (b) CTR1 The explanation: CTR1 is the negative regulator of ethylene response. |
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| 142. |
Which of the following statements is true about transmembrane electrical potential?(a) The chemical gradient drives Cl^– and K^+ inwards(b) The electrical gradient drives Na^+ and Ca^+2 inwards(c) The chemical gradient drives Na^+ and Ca^+2 inwards and K^+ outward(d) The chemical gradient drives Cl^– and K^+ outwards |
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Answer» Right option is (c) The chemical gradient drives Na^+ and Ca^+2 inwards and K^+ outward The explanation is: The chemical gradient drives Na^+ and Ca^+2 inwards and K^+ outward, electrical gradient drives Cl^–. |
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| 143. |
Which of the following acts as a passive electrical insulator?(a) Myelin sheath(b) Plasma membrane(c) Inner mitochondrial membrane(d) Outer mitochondrial membrane |
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Answer» The correct option is (a) Myelin sheath To explain: Myelin sheath acts as a passive electrical insulator. |
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| 144. |
Signal molecule fits the binding site on its complementary receptor called as _____________(a) Specificity(b) Amplification(c) Integration(d) Cooperativity |
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Answer» Right answer is (a) Specificity Explanation: Number of affected molecules increases geometrically in an enzyme cascade in amplification. A regulatory outcome result from integrated input from both receptors is in integration. |
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| 145. |
Which of the following transports only one kind of substrate?(a) Uniport carriers(b) Symport carriers(c) Antiport carriers(d) Membrane proteins |
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Answer» Right answer is (a) Uniport carriers For explanation I would say: Symport carriers move two or more substrates in the same direction across the membrane. Antiport carriers move substrates in the opposite direction. |
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| 146. |
Which of the following are stimulated to become membrane associated upon binding of insulin to the insulin receptor?(a) PH-domain(b) PTB(c) SH3(d) SH2 |
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Answer» Correct answer is (a) PH-domain Explanation: PH domain is stimulated to become membrane associated upon binding of insulin to the insulin receptor. |
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| 147. |
Which of the following is false about lipids?(a) They are either strongly hydrophobic or amphipathic(b) They are more soluble in water(c) Extraction of lipids from tissues require organic solvents(d) They are insoluble in water |
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Answer» Correct choice is (b) They are more soluble in water Easy explanation: Lipids are least soluble in water. They are amphipathic. |
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| 148. |
Which of the following type structure contains all the three glycosphingolipids?(a) B structure(b) A structure(c) O structure(d) AB structure |
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Answer» Correct option is (c) O structure Easy explanation: Type O structure has all three glycosphingolipids. |
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| 149. |
How are the intrinsic proteins in cell membrane distributed?(a) Uniform(b) Random(c) Symmetric(d) Asymmetric |
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Answer» The correct option is (d) Asymmetric For explanation I would say: Intrinsic proteins in cell membrane are distributed symmetrically. |
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| 150. |
Which of the following serves as a specific binding site for the proteins involved in membrane fusion during exocytosis?(a) Phosphatidylinositol(b) Phosphatidylinositol 4, 5-biphosphate(c) Phosphatidylinositol 3, 5-biphosphate(d) Phosphatidylinositol 3, 4-biphosphate |
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Answer» The correct option is (b) Phosphatidylinositol 4, 5-biphosphate Best explanation: Phosphatidylinositol 4, 5-biphosphate in the cytoplasmic face of plasma membranes serves as a specific binding site for certain cytoskeletal proteins and for some soluble proteins involved in membranes fusion during exocytosis. |
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