InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
Most major metabolic pathways are considered mainly either anabolic or catabolic. Which of the following pathway is most correctly considered to be amphibolic? (A) Citric acid cycle(B) Gluconeogenesis (C) Lipolysis (D) Glycolysis |
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Answer» (A) Citric acid cycle |
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| 102. |
Nicotine present in tobacco is a/an (A) Alkaloid (B) Terpene (C) Steroid (D) Protein |
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Answer» Nicotine present in tobacco is a/an Alkaloid. |
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| 103. |
A synthetic nucleotide analogue, used in organ transplantation as a suppressor of immunologic rejection of grafts is (A) Theophylline (B) Cytarabine (C) 4-Hydroxypyrazolopyrimidine (D) 6-Mercaptopurine |
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Answer» (D) 6-Mercaptopurine |
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| 104. |
The compound which has the lowest density is |
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Answer» (A) Chylomicron |
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| 105. |
The starting material for ketogenesis is (A) Acyl-CoA (B) Acetyl-CoA (C) Acetoacetyl-CoA (D) Malonyl-CoA |
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Answer» (C) Acetoacetyl-CoA |
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| 106. |
Two molecules of acetyl-CoA condense to form acetoacetyl-CoA catalysed by (A) Thiolase (B) Kinase (C) Reductase (D) Isomerase |
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Answer» The Correct option is (A) Thiolase |
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| 107. |
The source of all the carbon atoms in cholesterol is (A) Acetyl-CoA (B) Bicarbonate (C) Propionyl-CoA (D) Succinyl-CoA |
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Answer» (A) Acetyl-CoA |
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| 108. |
The formation of ∆2-trans-enoyl-CoA from acyl-CoA requires the enzyme: (A) Acyl-CoA synthetase (B) Acyl-CoA dehydrogenase (C) 3-Hydroxy acyl-CoA dehydrogenase (D) Thiolase |
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Answer» (B) Acyl-CoA dehydrogenase |
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| 109. |
An example of enzyme inhibition: (A) Reversible inhibition (B) Irreversible inhibition (C) Allosteric inhibition (D) All of these |
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Answer» Correct option (D) All of these Explanation: There are three broad categories of enzyme inhibition: (a) Reversible inhibition: The inhibitor binds noncovalently with the enzyme and the inhibition is reversible. Competitive, non-competitive and uncompetitive come under this category. (b) Irreversible inhibition: The inhibitor covalently binds with the enzyme which is irreversible. (c) Allosteric inhibition: Certain enzymes possessing allosteric sites are regulated by allosteric effectors |
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| 110. |
The Km of the enzyme giving the kinetic data as below is (A) –0.50 (B) –0.25 (C) +0.25 (D) +0.33 |
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Answer» The Km of the enzyme giving the kinetic data as below is +0.33. |
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| 111. |
Jamaican vomiting sickness is due to inactivation of the enzyme (A) Pyruvate carboxylase (B) Acyl-Co-A synthetase (C) Acyl-Co-A dehydrogense (D) Thiolase |
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Answer» (C) Acyl-Co-A dehydrogense |
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| 112. |
The enzyme deficient in Sandhoff’s disease is (A) α-Fucosidase (B) Hexosaminidase A and B (C) β-Galactosidase (D) β-Glucosidase |
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Answer» (B) Hexosaminidase A and B |
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| 113. |
Wolman’s disease is due to deficiency of (A) Cholesteryl ester hydrolase (B) Hexosaminidase A (C) α-Fucosidase (D) Arylsulphatase A |
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Answer» (A) Cholesteryl ester hydrolase |
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| 114. |
Phospholipase C attacks the ester bond liberating 1, 2-diacylglycerol and a phosphoryl base at position (A) 1 (B) 2 (C) Both (A) and (B) (D) 3 |
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Answer» The Correct option is (D) 3 |
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| 115. |
In pentose phosphate pathway, D-ribulose5-phosphate is converted to D-ribose-5- phosphate by the enzyme: (A) Fumarase (B) Ketoisomerase (C) G-6-PD (D) Epimerase |
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Answer» (B) Ketoisomerase |
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| 116. |
The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate |
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Answer» (B) Ribulose-5-phosphate |
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| 117. |
The pentose phosphate pathway protects erythrocytes against hemolysis by assisting the enzyme: (A) Superoxide dismutase (B) Catalase (C) Glutathionic peroxidase (D) Cytochrome oxidase |
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Answer» (C) Glutathionic peroxidase |
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| 118. |
The transketolase enzyme in the pentose phosphate pathway requires the B vitamin. (A) Pantothenic acid (B) Thiamin (C) Riboflavin (D) Nicotinic acid |
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Answer» The transketolase enzyme in the pentose phosphate pathway requires the B vitamin Thiamin. |
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| 119. |
The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation |
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Answer» (A) Increased by Insulin |
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| 120. |
Pentose phosphate pathway is of significance because it generates (A) NADPH for reductive synthesis (B) Regenerates glucose 6-phosphate (C) Generates fructose 6-phosphate (D) Forms glyceraldehyde 3-phosphate |
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Answer» (A) NADPH for reductive synthesis |
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| 121. |
The normal value of CPK in serum varies between (A) 4–60 IU/L (B) 60–250 IU/L (C) 4–17 IU/L (D) > 350 IU/L |
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Answer» (A) 4–60 IU/L |
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| 122. |
Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase |
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Answer» (A) Lysosomal α-1→4 and 1→6-glucosidase |
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| 123. |
All of the following are iron-containing enzymes except (A) Carbonic anhydrase (B) Catalase (C) Peroxidase (D) Cytochrome oxidase |
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Answer» (A) Carbonic anhydrase |
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| 124. |
Biotin is a coenzyme for (A) Pyruvate dehydrogenase (B) Pyruvate carboxylase (C) PEP carboxykinase (D) Glutamate pyruvate transminase |
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Answer» (B) Pyruvate carboxylase |
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| 125. |
The synthesis of 3-hydroxy-3-methylglutaryl-CoA can occur (A) Only in mitochondria of all mammalian tissues (B) Only in the cytosol of all mammalian tissue (C) In both cytosol and mitochondria (D) In lysosomes |
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Answer» (C) In both cytosol and mitochondria |
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| 126. |
Glucose absorption is promoted by (A) Vitamin A (B) Thiamin (C) Vitamin C (D) Vitamin K |
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Answer» Glucose absorption is promoted by Thiamin. |
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| 127. |
The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP |
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Answer» The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is NAD. |
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| 128. |
The synthesis of fatty acids is often termed reductive synthesis. (A) NADP+ (B) NADH (C) FADH2 (D) NADPH |
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Answer» The synthesis of fatty acids is often termed reductive synthesis NADPH. |
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| 129. |
In most metabolic pathways, all needed enzymes are arranged together in a multienzyme complex within a (A) Solution of ATP (B) Membrane (C) Quanternary protein (D) Coenzyme |
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Answer» (B) Membrane |
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| 130. |
An enzyme promotes a chemical reaction by (A) Lowering the energy of activation (B) Causing the release of heat which acts as a primer (C) Increasing molecular motion(D) Changing the free energy difference between substrate and product |
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Answer» (A) Lowering the energy of activation |
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| 131. |
When [s] is equal to Km, which of the following conditions exist? (A) Half the enzyme molecules are bound to substrate (B) The velocity of the reaction is equal to Vmax (C) The velocity of the reaction is independent of substrate concentration (D) Enzyme is completely saturated with substrate |
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Answer» (A) Half the enzyme molecules are bound to substrate |
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| 132. |
An inorganic ion required for the activity of an enzyme is known as (A) Activator (B) Cofactor (C) Coenzyme (D) None of these |
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Answer» (B) Cofactor |
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| 133. |
Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these |
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Answer» (D) All of these |
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| 134. |
Regulation of some enzymes by covalent modification involves addition or removal of (A) Acetate (B) Sulphate (C) Phosphate (D) Coenzyme |
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Answer» (C) Phosphate |
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| 135. |
A competitive inhibitor of an enzyme has which of the following properties? (A) It is frequently a feedback inhibitor (B) It becomes covalently attached to an enzyme (C) It decreases the Vmax (D) It interferes with substrate binding to the enzyme |
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Answer» (D) It interferes with substrate binding to the enzyme |
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| 136. |
Which of the following regulatory reactions involves a reversible covalent modification of an enzyme? (A) Phosphorylation of serine OH on the enzyme (B) Allosteric modulation (C) Competitive inhibition (D) Non-competitive inhibition |
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Answer» (A) Phosphorylation of serine OH on the enzyme |
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| 137. |
The rate of most enzyme catalysed reactions changes with pH. As the pH increases, this rate (A) reaches a minimum, then increases (B) reaches a maximum, then decreases (C) increases (D) decreases |
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Answer» (B) reaches a maximum, then decreases |
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| 138. |
Synthesis of phosphatidylinositol by transfer of inositol to CDP diacylglycerol is catalysed by the enzyme: (A) CTP phosphatidate cytidyl transferase (B) Phosphatidate phosphohydrolase (C) CDP-diacylglycerol inositol transferase (D) Choline kinase |
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Answer» (C) CDP-diacylglycerol inositol transferase |
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| 139. |
Isoenzymes are (A) Chemically, immunologically and electrophoretically different forms of an enzyme (B) Different forms of an enzyme similar in all properties (C) Catalysing different reactions (D) Having the same quaternary structures like the enzymes |
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Answer» (A) Chemically, immunologically and electrophoretically different forms of an enzyme |
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| 140. |
An example of ligases is (A) Succinate thiokinase (B) Alanine racemase (C) Fumarase (D) Aldolase |
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Answer» (A) Succinate thiokinase |
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| 141. |
Kinetics of an allosteric enzyme are explained by (A) Michaelis-Menten equation (B) Lineweaver-Burk plot (C) Hill plot (D) All of these |
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Answer» (C) Hill plot |
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| 142. |
Zymogen is a (A) Vitamin (B) Enzyme precursor (C) Modulator (D) Hormone |
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Answer» (B) Enzyme precursor |
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| 143. |
In plants, enzymes occur in (A) Flowers only (B) Leaves only (C) All living cells (D) Storage organs only |
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Answer» (C) All living cells |
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| 144. |
An enzyme can accelerate a reaction up to (A) 1010 times (B) 101 times (C) 10100 times (D) 10 times |
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Answer» (A) 1010 times |
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| 145. |
Enzymes accelerate the rate of reactions by (A) Increasing the equilibrium constant of reactions (B) Increasing the energy of activation (C) Decreasing the energy of activation (D) Decreasing the free energy change of the reaction |
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Answer» (C) Decreasing the energy of activation |
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| 146. |
In which of the following types of enzymes, water may be added to a C—C double bond without breaking the bond? (A) Hydrolase (B) Hydratase (C) Hydroxylase (D) Oxygenase |
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Answer» (A) Hydrolase |
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| 147. |
Neimann-Pick disease is due to the deficiency of the enzyme: (A) Hexosaminidase A and B (B) Ceramidase (C) Ceramide lactosidase (D) Sphingomyelinase |
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Answer» (D) Sphingomyelinase |
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| 148. |
Niemann-Pick disease is due to deficiency of the enzyme (A) Ceramidase (B) Glucocerebrosidase (C) Galactocerebrosidase (D) Sphingomyelinase |
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Answer» (D) Sphingomyelinase |
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| 149. |
The enzyme ceramidase is deficient in (A) Farber’s disease (B) Fabry’s disease (C) Sandhoff’s disease(D) Refsum’s disease |
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Answer» (A) Farber’s disease |
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| 150. |
Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis |
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Answer» (B) Increased fatty acid oxidation |
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