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Acidic drugs like imipramine, lidocaine bind to alpha 1 Acid Glycoprotein.(a) True(b) FalseThis question was posed to me in an online interview.My enquiry is from Plasma Protein Drug Binding in chapter Protein Binding of Drugs of Drug Biotechnology

Answer»

Correct option is (b) False

Easy EXPLANATION: Alpha 1 ACID GLYCOPROTEIN is also called as orsomucoid. It has a molecular weight of 44,000 and a plasma concentration of range 0.04-0.1%. It BINDS basic drugs like imipramine, lidocaine, quinidine, etc.



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