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Ataxia talengictesia is due to the defect in which of the following?(a) P53(b) Mdm2(c) Cdc25(d) Mad2The question was asked by my college professor while I was bunking the class.The doubt is from Cell Cycle Stages topic in chapter Cancer Biology & Methods in Cytogenetics of Cytogenetics

Answer»

Correct answer is (B) Mdm2

Easy explanation: The defect in Mdm2 when it is unable to phosphorylate P53 in response to DNA damage causes ataxia talengictesia. It is a genetic DISORDER that often leads to CANCER.



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