CPSF and CStF bind to ____________(a) AAUAAA and G/U box respectively and bind is very strong(b) G/U box and AAUAAA respectively and bind is very strong(c) G/U box strongly but weakly AAUAAA(d) AAUAAA weakly but stabilization occurs after G/U bindingThe question was posed to me in an interview for job.The doubt is from Post-Transcriptional Modification in division Gene Expression : Transcription Prokaryotes of Cytogenetics

CPSF and CStF bind to ____________(a) AAUAAA and G/U box respectively

1.	CPSF and CStF bind to ____________(a) AAUAAA and G/U box respectively and bind is very strong(b) G/U box and AAUAAA respectively and bind is very strong(c) G/U box strongly but weakly AAUAAA(d) AAUAAA weakly but stabilization occurs after G/U bindingThe question was posed to me in an interview for job.The doubt is from Post-Transcriptional Modification in division Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» Correct OPTION is (d) AAUAAA weakly but stabilization occurs after G/U binding For EXPLANATION: CPSF binds to AAUAAA but the interaction is weak. This interaction is strengthened by CStF binding to G/U box and further stabilization occurs at CFI and CFII binding.

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