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Which of the following is not a common mode of histone modification in eukaryotes?(a) Methylation(b) Phosphortlation(c) Sulphonation(d) UbiquitinylationThis question was posed to me in final exam.Question is taken from Transcription in Eukaryotes : Chromatin Remodelling in portion Gene Expression : Transcription Prokaryotes of Cytogenetics

Answer»

Correct answer is (c) Sulphonation

The BEST explanation: The POSITIVELY charged N-termini of histone is modified by the PHOSPHORYLATION, ubiquitinylation, methylation and also acetylation processes in order to shield its POSITIVE charges.



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