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Downregulation of caspase 3 can lead to ovarian cancer.(a) True(b) FalseI had been asked this question in an interview for job.Origin of the question is Apoptosis and Cancer in section Cancer Biology & Methods in Cytogenetics of Cytogenetics

Answer»

Correct choice is (a) True

To EXPLAIN I would say: It has been reported that caspase-3 mRNA levels are appreciably downregulated in breast, ovarian, and cervical tumours. LOW levels of caspases or IMPAIRMENT in caspase function MAY LEAD to decreased apoptosis.



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