Downregulation of caspase 9 is seen in ________________(a) Melanoma(b) Breast cancer(c) Colorectal cancer(d) Lung cancerI have been asked this question during an internship interview.I'm obligated to ask this question of Apoptosis and Cancer topic in chapter Cancer Biology & Methods in Cytogenetics of Cytogenetics

Downregulation of caspase 9 is seen in ________________(a) Melanoma(b)

1.	Downregulation of caspase 9 is seen in ________________(a) Melanoma(b) Breast cancer(c) Colorectal cancer(d) Lung cancerI have been asked this question during an internship interview.I'm obligated to ask this question of Apoptosis and Cancer topic in chapter Cancer Biology & Methods in Cytogenetics of Cytogenetics
Answer» Correct answer is (c) Colorectal cancer Explanation: Reduced functioning of caspases may PREVENT APOPTOSIS THUS leading to cancer. Down regulation of CASPASE 12 is seen mostly in case of colorectal cancers.

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