How does Eicosapentaenoic acid functions to decrease the inflammation rate?(a) Decrease Prostaglandin production(b) Don’t form prostaglandin(c) Induce the formation of prostaglandins at certain times(d) The prostaglandins, thromboxane produced from EPA are less activeI have been asked this question in an online interview.The query is from Drug Addiction and Abuse in section Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

How does Eicosapentaenoic acid functions to decrease the inflammation

1.	How does Eicosapentaenoic acid functions to decrease the inflammation rate?(a) Decrease Prostaglandin production(b) Don’t form prostaglandin(c) Induce the formation of prostaglandins at certain times(d) The prostaglandins, thromboxane produced from EPA are less activeI have been asked this question in an online interview.The query is from Drug Addiction and Abuse in section Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology
Answer» The correct option is (d) The prostaglandins, THROMBOXANE produced from EPA are less active The explanation is: EPA is found in fish oil. It acts as a substrate for cyclooxygenases and lipoxygenases thus it competing with arachidonic acid for the enzymes. The prostaglandins, thromboxanes, and LEUKOTRIENES produced from EPA are less active than AA METABOLITES. These products then compete with products of AA metabolism for SHARED target receptors.

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