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How many H^+ ions are transported by the vacuole H+-ATPase pump and the vacuole H+-phosphatase pump per hydrolysis of ATP and pyrophosphate respectively?(a) 1, 1(b) 1, 2(c) 2, 1(d) 2, 2This question was addressed to me in an interview.This is a very interesting question from Movement of Substances Across Cell Membranes in chapter Cellular Membranes of Cell Biology

Answer»

The correct option is (C) 2, 1

The explanation is: The VACUOLE H+-ATPase pump and the vacuole H^+-phosphatase pump are membrane proteins on the vacuole membrane that helps in the active transport of H^+ IONS inside the vacuole. With the HYDROLYSIS of one ATP molecule, two H^+ ions can pass through the H^+-ATPase pump. HOWEVER, with the hydrolysis of one pyrophosphate molecule, one H^+ ion can pass through the H+-pyrophospatase pump.



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