1.

Which of the following facilitates binding of positively charged amino acid residues?(a) Phosphatidyl choline (PC)(b) Phosphatidyl serine (PS)(c) Phosphatidyl ethanolamine (PE)(d) Phosphatidyl inositol(PI)I have been asked this question in an interview for internship.I need to ask this question from Chemical Composition of Membranes in division Cellular Membranes of Cell Biology

Answer»

Right OPTION is (B) Phosphatidyl serine (PS)

Easiest explanation: PS, concentrated in the inner leaflet of cell membrane, has a negative charge at physiologic pH and thus binds positively charged amino acid residues of lysine and arginine. The appearance of PS on the outer surface of aging lymphocytes marks the CELLS for destruction by MACROPHAGES. Appearance of PSon the outer surface of platelets can lead to BLOOD coagulation.



Discussion

No Comment Found

Related InterviewSolutions