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In FISH technology, which fluorescence confirms a BCR/ABL translocation?(a) Red signal(b) Green signal(c) Yellow signal(d) Orange signalThis question was posed to me in class test.This question is from Genes, Chromosomes and Genomes topic in chapter Bioenergetics, Enzymes, Metabolism, Genes, Chromosomes and Genomes of Cell Biology

Answer»

Right ANSWER is (C) YELLOW signal

The BEST EXPLANATION: In FISH, the green signal indicates presence of the BCR gene and the red signal indicate the presence of the ABL gene. The red-green fusion (yellow) signal confirms a BCR/ABL translocation.



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