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The DNA binding proteins bind at the _______________(a) Minor groove(b) Major groove(c) Phosphate molecules(d) Pentose sugarsI got this question in an internship interview.The above asked question is from Genes, Chromosomes and Genomes in division Bioenergetics, Enzymes, Metabolism, Genes, Chromosomes and Genomes of Cell Biology

Answer» RIGHT answer is (b) Major groove

For explanation: The DNA double strands are present as a double-helix as they wound around each another. DUE to base stacking, ALTERNATIVE minor and major grooves are formed in the helix. Major groove provide the site for DNA protein binding.


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