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In mice the expression of Igf2 and H199 is only controlled by methylation.(a) True(b) FalseI had been asked this question in homework.The doubt is from Silencing and Genomic Imprinting topic in section Regulating Gene Expression in Eukaryotes of Cytogenetics

Answer»

Right answer is (b) False

The best EXPLANATION: In addition to methylation the CONTROL is achieved by the presence of an insulator CTCB that HELPS by PREVENTING the enhancer interaction of IGF2 in the maternal chromosome.



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