1.

Which of the following is not a normal processing step of the tRNA?(a) The 3’ end U is replaced by CCA(b) The Purines are methylated and isopentyl groups are transferred to them(c) The 3’ OH is methylated(d) U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridineI had been asked this question in a job interview.My query is from RNA Processing Control in section Regulating Gene Expression in Eukaryotes of Cytogenetics

Answer»

The correct choice is (c) The 3’ OH is methylated

The BEST explanation: The 2’-OH groups of some bases are MODIFIED in the tRNA and not the 3’-OH. White the remaining modifications of the tRNA TRANSCRIPT are necessary.



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