Loosening the binding between polymerase and non-specific site is important to confer higher specificity. In Bacillus subtilis what is responsible for this action?(a) Sigma factor(b) Alpha subunit(c) Beta subunit(d) Delta subunitThis question was posed to me by my school teacher while I was bunking the class.I want to ask this question from Transcription in Prokaryotes : Sigma Factor topic in portion Gene Expression : Transcription Prokaryotes of Cytogenetics

Loosening the binding between polymerase and non-specific site is impo

1.	Loosening the binding between polymerase and non-specific site is important to confer higher specificity. In Bacillus subtilis what is responsible for this action?(a) Sigma factor(b) Alpha subunit(c) Beta subunit(d) Delta subunitThis question was posed to me by my school teacher while I was bunking the class.I want to ask this question from Transcription in Prokaryotes : Sigma Factor topic in portion Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» The correct option is (d) Delta subunit To elaborate: While σ^70 in E. coli has an extra 245 amino acid that helps it to LOOSEN the polymerase from non-specific SITE, σ^43 in BACILLUS subtilis lacks it. Thus, it needs another subunit of core polymerase- delta subunit to perform this function.

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