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M cyclin CDK _________________ cdc20 and ______________ Hct1?(a) Activates, activates(b) Activates, inactivates(c) Inactivates, activates(d) Inactivates, activatesI had been asked this question in an online interview.Asked question is from Cell Cycle Stages in section Cancer Biology & Methods in Cytogenetics of Cytogenetics

Answer»

The correct CHOICE is (b) Activates, inactivates

Best explanation: Both Cdc20 and Hct1 are APC ligases which HELP in escape from mitosis by destruction of M CDK, but cdc20 is activated by M CYCLIN – CDK by while Hct1 is INACTIVATED by the same through phsphorylation.



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