M cyclin cdk is activated by positive feedback loop.(a) True(b) FalseThe question was posed to me in examination.My question is from Cell Cycle Stages topic in division Cancer Biology & Methods in Cytogenetics of Cytogenetics

M cyclin cdk is activated by positive feedback loop.(a) True(b) FalseT

1.	M cyclin cdk is activated by positive feedback loop.(a) True(b) FalseThe question was posed to me in examination.My question is from Cell Cycle Stages topic in division Cancer Biology & Methods in Cytogenetics of Cytogenetics
Answer» Right option is (a) True The explanation is: The M-cyclin Cdk when bound to sic1 in turn also CAUSES SLIGHT transcription of M cyclin gene. Increasing CONCENTRATION of M cyclin further INCREASES its activity. This works as a positive FEEDBACK loop which ultimately leads to M cdk activation.

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