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P53 binds to MAD2.(a) True(b) FalseI have been asked this question in an online quiz.Asked question is from Cell Cycle Stages topic in chapter Cancer Biology & Methods in Cytogenetics of Cytogenetics

Answer»

Right answer is (b) False

To explain: P53 binds to Mdm2 in NORMAL cell which destroys the p53 leading to its REDUCTION in concentration. On the other HAND Mad2 bind to kinetochores that are not ATTACHED to microtubules.



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