Penicillin has short plasma half-life although it can bind to plasma protein rigidly.(a) True(b) FalseThe question was posed to me by my college professor while I was bunking the class.The question is from Factors Affecting Protein Drug Binding in portion Protein Binding of Drugs of Drug Biotechnology

Penicillin has short plasma half-life although it can bind to plasma p

1.	Penicillin has short plasma half-life although it can bind to plasma protein rigidly.(a) True(b) FalseThe question was posed to me by my college professor while I was bunking the class.The question is from Factors Affecting Protein Drug Binding in portion Protein Binding of Drugs of Drug Biotechnology
Answer» The correct choice is (a) True The explanation: PENICILLIN has a short plasma half-life. Though it can rigidly bind to the plasma still it has short ELIMINATION half live. This is because equilibration occurs between the free and the bound PROTEIN and the free drug is equally rapidly excreted by active secretion in renal TUBULES.

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