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Quasi – steady state in fed batch is when?(a) Growth rate remains constant(b) Dilution remains constant(c) Growth rate changes variably(d) μ remains constantI had been asked this question in an interview for job.My doubt stems from Fed Batch Culture in division Microbial Growth Kinetics of Bioprocess Engineering

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Right ANSWER is (c) Growth RATE changes variably

Easy explanation: The MAJOR difference between the steady state of a CHEMOSTAT and the quasi steady state of a fed batch culture is that μ is constant in the chemostat but decreases in fed-batch. However, in the genuine steady state of a chemostat, dilution rate and growth rate are constant whereas in a fed-batch quasi steady state they change over the time of fermentation.



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