Repressors are active only when they are at the proximity of the RNA polymerase as they directly associate with the pre-initiation complex. State whether this is true or false.(a) True(b) FalseI had been asked this question in unit test.The question is from Transcription in Eukaryotes : Activators and Repressors in division Gene Expression : Transcription Prokaryotes of Cytogenetics

Repressors are active only when they are at the proximity of the RNA p

1.	Repressors are active only when they are at the proximity of the RNA polymerase as they directly associate with the pre-initiation complex. State whether this is true or false.(a) True(b) FalseI had been asked this question in unit test.The question is from Transcription in Eukaryotes : Activators and Repressors in division Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» Correct answer is (b) False The explanation: Although often repressors DIRECTLY associate with RNA POLYMERASES it can also act by the means of a mediator as ENHANCERS do. So, they could be close or far from the transcription start site.

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