I am using Avast. I RECENTLY downloaded Spyware Terminator with Clam Antivirus. Can I run them both at the same time, or will that cause problems? I know you're not supposed to have two AV's.not an expert on security, but I believe the problem with running two antivirus PROGRAMS at the same time actually refers to the real-time protection. On one hand, you have on-demand anti-virus, like Malwarebytes, where they only run when you call on them.... On the other hand you have real-time antivirus, where they constantly monitor your system... It's this type of antivirus is where you do not want two of them running simultaneously...You could disable the real-time protection in one of them however, if it is optional...Like AVG, I know AVG lets you disable the real-time protection.....also known as "resident shield"

If I were you I'd pick the anti-virus program with the best ratings as far as real-time protection is CONCERNED and let that one DOMINATE your system, while the others just lurk in the background and run manual scans with them as needed..

When I run scans or suspect a virus, I always use multiple on-demand programs...They are already installed on my system so all I have to do is update them when I need them and not worry about downloading and installing.. you cannot run 2 anti-virus you should delete 1 , i would keep avst , why do you need 2I think spyware terminator adds the realtime mode to clamwin antivirus that otherwise clamwin would not have.

I would just keep Avast on, updated and running and forget about Clamwin unless you want to keep it handy in somewhere like a USB stick for backup virus scans.Spyware Terminator is a fine addition, and it won't interfere with AV program.
Clam doesn't run in real time. It's on demand scanner, so it'll COEXIST with others as well.however .... according to Spyware Terminator's features list

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Spyware Terminator has included the popular award winning open-source antivirus, Clam AntiVirus (ClamAV), for optional integration to achieve a higher level of security. ClamAV can be integrated into spyware scans, updates and the real-time protection.