The extent of drug-protein binding can change with both changes in protein and drug concentration.(a) True(b) FalseThe question was posed to me by my college professor while I was bunking the class.This intriguing question originated from Factors Affecting Protein Drug Binding topic in section Protein Binding of Drugs of Drug Biotechnology

The extent of drug-protein binding can change with both changes in pro

1.	The extent of drug-protein binding can change with both changes in protein and drug concentration.(a) True(b) FalseThe question was posed to me by my college professor while I was bunking the class.This intriguing question originated from Factors Affecting Protein Drug Binding topic in section Protein Binding of Drugs of Drug Biotechnology
Answer» The CORRECT answer is (a) True For explanation: The concentration of drug that binds to HSA do not have much influence on HA, since any concentration of drug in LESS than the concentration of HSA. The therapeutic concentration of lidocaine can saturate AAG with which it binds as the concentration of AAG is much less in comparison to that of HSA in blood.

Discussion

No Comment Found

Related InterviewSolutions

What kind of graph is shown in the picture?(a) Direct plot(b) Scatchard plot(c) Double reciprocal plot(d) Michele’s menten plotI got this question during an online interview.This question is from Factors Affecting Protein Drug Binding in portion Protein Binding of Drugs of Drug Biotechnology
In the equation X= Vd C, what does X stands for?(a) Amount of drug in the blood(b) Amount of drug in plasma(c) Amount of drug in the tablet(d) Amount of drug in the bodyThis question was addressed to me during an internship interview.Query is from Factors Affecting Protein Drug Binding in section Protein Binding of Drugs of Drug Biotechnology
Which one of the following is the correct order of the drugs binding to various plasma protein?(a) Albumin > alpha-1 acid glycoprotein > globulins> lipoproteins(b) Albumin > globulins> lipoproteins > alpha-1 acid glycoprotein(c) Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins(d) Albumin > lipoproteins> globulins> alpha-1 acid glycoproteinI got this question during an interview.I would like to ask this question from Plasma Protein Drug Binding in portion Protein Binding of Drugs of Drug Biotechnology
Which of the following factors for protein drug binding is a drug interaction factor?(a) Competition between drugs for the binding site(b) Age(c) Physicochemical characteristics of a drug(d) Physicochemical characteristics of the protein or binding agentThis question was posed to me at a job interview.My question is from Factors Affecting Protein Drug Binding topic in chapter Protein Binding of Drugs of Drug Biotechnology
Which of the given drugs bind to Α1 globulin?(a) Steroidal drugs(b) Vitamins A, D, E, K(c) Ferrous ions(d) CarotenoidsThis question was posed to me in an online interview.I'm obligated to ask this question of Plasma Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology
Which drug accumulate in adipose tissue?(a) Arsenicals(b) Tetracycline(c) Halogenated hydrocarbons(d) Lipophilic drugThe question was asked in an interview for internship.The query is from Tissue Binding of Drugs topic in section Protein Binding of Drugs of Drug Biotechnology
Which of the following drugs are responsible for retinopathy?(a) Acidic drugs like imipramine(b) Basic drugs like imipramine(c) Halogenated hydrocarbons(d) ChloroquinineI have been asked this question during an online exam.This interesting question is from Tissue Binding of Drugs in portion Protein Binding of Drugs of Drug Biotechnology
Which of the following drugs accumulate in skin?(a) Acidic drugs like imipramine(b) Basic drugs like imipramine(c) Halogenated hydrocarbons(d) ChloroquineI got this question in an international level competition.My question is taken from Tissue Binding of Drugs topic in chapter Protein Binding of Drugs of Drug Biotechnology
Which of the given drugs bind to Β2 globulin?(a) Steroidal drugs(b) Vitamins A, D, E, K(c) Ferrous ions(d) CarotenoidsThis question was posed to me in semester exam.My question is based upon Plasma Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology
Acidic drugs like imipramine, lidocaine bind to alpha 1 Acid Glycoprotein.(a) True(b) FalseThis question was posed to me in an online interview.My enquiry is from Plasma Protein Drug Binding in chapter Protein Binding of Drugs of Drug Biotechnology

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment