The poly a tail protects the 3’ end from____________(a) 5’->3’ exonuclease(b) 3’->5’ exonuclease(c) Translation(d) ExportI have been asked this question during an interview for a job.I want to ask this question from Post-Transcriptional Modification in division Gene Expression : Transcription Prokaryotes of Cytogenetics

The poly a tail protects the 3’ end from____________(a) 5’->3’ e

1.	The poly a tail protects the 3’ end from____________(a) 5’->3’ exonuclease(b) 3’->5’ exonuclease(c) Translation(d) ExportI have been asked this question during an interview for a job.I want to ask this question from Post-Transcriptional Modification in division Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» Correct choice is (b) 3’->5’ exonuclease Explanation: The 3’ END of the RNA is susceptible to chewing by 3’->5’ exonucleases. So, the poly A TAIL acts as a safeguard which EVEN if chewed partly will protect the valuable information of the RNA. This in PLACE of inhibition rather promotes the next steps LIKE transcription and export.

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