We know that lactose has a positive impact on the activity of the lac operon. Tryptophan’s presence has a ________________(a) Positive feedback(b) Negative feedback(c) No difference(d) Highly positive impactI had been asked this question during an interview.My doubt is from Operons : Trp in division Gene Expression : Transcription Prokaryotes of Cytogenetics

We know that lactose has a positive impact on the activity of the lac

1.	We know that lactose has a positive impact on the activity of the lac operon. Tryptophan’s presence has a ________________(a) Positive feedback(b) Negative feedback(c) No difference(d) Highly positive impactI had been asked this question during an interview.My doubt is from Operons : Trp in division Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» Right option is (b) Negative feedback Easiest explanation: Trp binding to the TRAP makes a trp-TRAP COMPLEX which binds to the RNA and stabilizes the TERMINATOR loop. Hence, TRYPTOPHAN’s PRESENCE has a negative feedback effect.

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