1.

What is the name of the drug binding site I of HSA?(a) Tamoxifen binding site(b) Digitoxin binding site(c) Diazepam binding site(d) Warfarin and azapropazone binding siteI have been asked this question in an internship interview.Origin of the question is Plasma Protein Drug Binding topic in division Protein Binding of Drugs of Drug Biotechnology

Answer»

The correct answer is (d) WARFARIN and azapropazone binding SITE

Easiest explanation: In the structure of HSA there 4 main binding sites for drugs. The site I am CALLED as the warfarin and azapropazone binding site. In this REGION, a large number of drugs can bind. For example several NSAIDs, phenytoin, sodium valproate, bilirubin.



Discussion

No Comment Found

Related InterviewSolutions