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Which antibiotic inhibits transcription elongation?(a) Rifampicin(b) Streptolydigin(c) Penicillin(d) TetracyclinThe question was asked at a job interview.Enquiry is from Transcription in Prokaryotes : Elongation in chapter Gene Expression : Transcription Prokaryotes of Cytogenetics

Answer»

The CORRECT option is (b) Streptolydigin

The best I can explain: Streptolydigin prevents elongation while Rifampicin prevents initiation. Penicillin and Tetracyclin ACT on the RIBOSOME and not on RNA polymerase although EVEN they ultimately inhibit protein SYNTHESIS.



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