Which drugs bind to HSA easily?(a) Cationic drug(b) Anionic drug(c) Lipophilic drug(d) Neutral drugI had been asked this question in an interview for internship.Query is from Factors Affecting Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology

Which drugs bind to HSA easily?(a) Cationic drug(b) Anionic drug(c) Li

1.	Which drugs bind to HSA easily?(a) Cationic drug(b) Anionic drug(c) Lipophilic drug(d) Neutral drugI had been asked this question in an interview for internship.Query is from Factors Affecting Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology
Answer» Right CHOICE is (b) Anionic drug To elaborate: Anionic or acidic drugs bind to HSA EASILY, for example, penicillin and sulphonamides. Cationic or BASIC drugs bind easily to alpha 1 acid glycoprotein, for example, imipramine and alprenolol. Neutral and unionized drugs bind to lipoproteins. Lipophilic drugs LOCALIZE more into adipose tissue.

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