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Which histone(s) are acted upon by HAT?(a) H1, H2(b) H3(c) H2A, H2B(d) H3, H4This question was posed to me during an interview for a job.I want to ask this question from Transcription in Eukaryotes : Chromatin Remodelling in section Gene Expression : Transcription Prokaryotes of Cytogenetics

Answer»

Right OPTION is (d) H3, H4

To elaborate: These are the TWO histone residues that are having lysine side chains available for ACETYLATION. On, HAT action they loosely bind to DNA allowing TRANSCRIPTION.



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