Which of the following is not a part of DISC complex?(a) Fas Ligand(b) Fas receptor(c) Cytochrome(d) Procaspase 8The question was posed to me in a national level competition.This is a very interesting question from Apoptosis and Cancer in division Cancer Biology & Methods in Cytogenetics of Cytogenetics

Which of the following is not a part of DISC complex?(a) Fas Ligand(b)

1.	Which of the following is not a part of DISC complex?(a) Fas Ligand(b) Fas receptor(c) Cytochrome(d) Procaspase 8The question was posed to me in a national level competition.This is a very interesting question from Apoptosis and Cancer in division Cancer Biology & Methods in Cytogenetics of Cytogenetics
Answer» The correct answer is (c) Cytochrome For EXPLANATION I would say: The DISC COMPLEX (death-inducing signalling complex ) consists of the fas ligand and receptor that FORMS the Death domain. This in turn aggregates and activates procaspase 8 to caspase 8. Cytochrome is not directly a part of DISC complex.

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