Which of the following is the proper sequence of assembly of factors on the branch poinr A?(a) U1-> U2-> U6(b) U2AF -> U2->BBP(c) BBP->U2AF->U2(d) BBP->U1->U2I had been asked this question in a job interview.My question is taken from Post-Transcriptional Modification in chapter Gene Expression : Transcription Prokaryotes of Cytogenetics

Which of the following is the proper sequence of assembly of factors o

1.	Which of the following is the proper sequence of assembly of factors on the branch poinr A?(a) U1-> U2-> U6(b) U2AF -> U2->BBP(c) BBP->U2AF->U2(d) BBP->U1->U2I had been asked this question in a job interview.My question is taken from Post-Transcriptional Modification in chapter Gene Expression : Transcription Prokaryotes of Cytogenetics
Answer» The correct ANSWER is (C) BBP->U2AF->U2 The explanation is: BBP stands for BRANCH point binding PROTEINS. In the branch site A 1st the U2AF binds followed by BBP then it is replaced by U2. Then U2 can INTERACT with U6 that replaced U1.

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