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Which of these is not true for TFIIH?(a) It is a helicase(b) On initiation the RNA pol starts transcribing leaving TFIIH at pre-IC(c) It has kinase activity(d) It is needed in Double Strand Break (DSB) repairThis question was posed to me in exam.This interesting question is from Transcription in Eukaryotes : Transcription Factors topic in division Gene Expression : Transcription Prokaryotes of Cytogenetics |
Answer» CORRECT answer is (b) On initiation the RNA pol starts transcribing leaving TFIIH at pre-IC To explain: TFIIH is NECESSARY for phosphorylating RNA pol and triggering its initiation. It moves on with the RNA pol after initiation starts. It ALSO acts as a HELICASE which is put to use during DSB REPAIR. |
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