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Which one of the following factors related to protein-drug binding is not related to drugs?(a) Physicochemical characteristics of a drug(b) The concentration of the drug in the body(c) The affinity of the drug for binding(d) Number of binding sites on the binding agentI had been asked this question in an international level competition.This interesting question is from Factors Affecting Protein Drug Binding in division Protein Binding of Drugs of Drug Biotechnology

Answer»

The correct OPTION is (d) Number of binding SITES on the binding AGENT

For explanation: There are many factors affecting protein-DRUG binding. The factors related to the drug, are PHYSICOCHEMICAL characteristics of a drug, concentration of the drug in the body, affinity of the drug for binding. A number of binding sites on the binding agent are related to the protein and other binding components.



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