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Which type of chromatography depends on the principle of size of particles?(a) Affinity chromatography(b) Gel- filtration chromatography(c) Ion- exchange chromatography(d) Multimodal chromatographyThe question was posed to me during an online exam.This interesting question is from Chromatography topic in chapter Unit Operations of Bioprocess Engineering

Answer»

The correct choice is (b) Gel- filtration CHROMATOGRAPHY

Easy EXPLANATION: Gel filtration chromatography, a type of SIZE exclusion chromatography, can be used to either FRACTIONATE molecules and COMPLEXES in a sample into fractions with a particular size range, to remove all molecules larger than a particular size from the sample, or a combination of both operations.



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