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Arrestins compete with ________________ for binding with G-protein coupled receptors.(a) Effectors(b) Primary messengers(c) Secondary messengers(d) G-proteinsThis question was addressed to me by my college professor while I was bunking the class.This interesting question is from Cell Signaling and Signal Transduction in division Cell Signaling and Signal Transduction of Cell Biology

Answer»

Correct CHOICE is (d) G-PROTEINS

Explanation: Arrestins are small group of proteins that bind to the G-protein coupled receptors. To bind to these receptors, the arrestins compete with heterotrimeric G-proteins. In the process of desensitization, ARRESTIN binding PREVENTS further ACTIVATION of the G-proteins.



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